The Archive

Earlier detection of pancreatic cancer is key to enabling wider access to curative treatment and reducing cancer deaths; however, screening is presently not viable. Latent indicators of pathology are evident in an individual's disease and blood test trajectories and may predict the development of pancreatic cancer. Longitudinal sequences of coded diagnoses and blood test values accrued by patients throughout their clinical interactions were used to train a custom Transformer-based neural network with a multi-head attention mechanism to predict risk of pancreatic cancer with a multi-year lead ...

Document-level translation remains one of the most challenging tasks for large language models, which are constrained by limited context windows that impede global cohesion, while simultaneously suffering from redundant contextual information that degrades translation quality. To address this, we propose a human-like long document translation agent called Loong, which leverages a 3E memory module (Essence-Exemplar-Entity) to store summaries, sentence pairs, and entity records as historical context. Instead of passively attending to all history, Loong performs deep reasoning to adaptively iden...

Large language models (LLMs) show promise in generating supportive responses for mental health queries, but improving their usefulness, empathy, and safety often requires substantial compute, expert input, and labeled data. At the same time, deploying proprietary, cloud-based models for mental health-related interactions raises important privacy and data-governance concerns, given the sensitivities. To address this challenge, we introduce LLUMI setup that can be hosted in-house within protected environments. LLUMI consists of two complementary components: a generation model (GM), which drafts...

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We address the task of generating physically accurate and visually faithful 4D Human-Object Interaction (HOI). Given a static 3D human and target object represented as 3D Gaussian Splats (3DGS), our goal is to synthesize dynamic scenes where the human actively engages with the object through actions, such as punching or kicking, in accordance with a given input text. To this end, we introduce PhyGenHOI, a novel framework that couples generative human motion with an explicit physical object simulation. We model the human as a semantic agent driven by a Motion Diffusion Model (MDM) and the obje...

Vision-Language Models (VLMs) have achieved substantial progress across a wide range of understanding and reasoning tasks, driven by large-scale image-text training aimed at multimodal fusion. Ideally, replacing a textual question with its rendered-image counterpart should leave model performance essentially unaffected. In practice, however, such modality substitution induces dramatic performance degradation. We attribute this "carrier sensitivity" issue to an inherent bias in current training corpora. Across prevalent datasets such as image captioning, VQA, OCR, and web-sourced interleaved d...

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Large Language Models (LLMs) must continuously learn and update knowledge to remain effective in dynamic real-world environments. While Low-Rank Adaptation (LoRA) is widely used for such memory updates, existing studies mainly rely on qualitative downstream evaluations, leaving the quantitative capacity limits and underlying dynamics of exact parametric memory largely unexplored. To bridge this gap, we employ LoRA as a controlled memory capacity probe within the latent space to systematically quantify exact parametric memory. We introduce the Parametric Memory Law, a robust power law linking ...

Natural human conversation is full-duplex and audio-visual: people simultaneously speak and listen while continuously interpreting and producing nonverbal cues, such as nods, smiles, and gestures. To support successful human-agent interaction, agents must model full-duplex audiovisual conversation; however, existing full-duplex benchmarks evaluate only speech. In this work, we present VideoFDB, the first benchmark to evaluate full-duplex audio-visual-to-audio-visual (AV2AV) conversational agents. VideoFDB contributes (i) 237 dyadic clips spanning 11 nonverbal conversational dynamics from real...

We study the contraction in Wasserstein distance of the coordinate ascent variational inference algorithm. This is shown to hold under a transport-information inequality at the fixed points and a functional smoothness condition. The results are general and sharp, allow for local convergence guarantees, hold for general smooth manifolds, and also in some non-smooth spaces. We consider applications to Bayesian Gaussian Mixture Models, and high-dimensional Bayesian Probit Regression, and Logistic Regression with Pólya-Gamma random variables (i.e. Jaakkola-Jordan's algorithm).

Large language models (LLMs) often solve a task when all instructions are given in a single prompt, but fail when the same information is revealed gradually across turns. When a clean FULL prompt and a RAW-SHARDED conversation contain the same complete user evidence, the model should still arrive at the same answer. We argue that a key reason for this gap is self-anchored drift: responses produced under partial information introduce unsupported assumptions, and those assumptions later distort the final answer. To reduce this effect, we propose Canonical-Context On-Policy Distillation (CCOPD)....

Drug synergy prediction (DSP) aims to identify efficacious drug combinations under various cellular contexts with different targets. However, the continual emergence of novel compounds results in variations in molecular scaffolds and sizes, causing drug synergy data to exhibit out-of-distribution (O.O.D.) shifts with respect to topological structure. Existing works rely on in-distribution (I.D.) assumption, failing to handle the O.O.D. shifts. To solve this problem, we study out-of-distribution generalized drug synergy prediction through a graph large language model for the first time. Nevert...

Current plan-based reasoning methods improve large language models (LLMs) by inserting a planning stage before execution, giving rise to the question $\rightarrow$ plan $\rightarrow$ cot paradigm. While effective, a closer examination reveals an inherent paradigm-level gap: both the planning and its execution stages decide how to solve a problem, while the prior question of what to solve; recognizing the problem type, the applicable tools, and the foreseeable pitfalls; remains entirely implicit. To bridge this gap, we propose PPC (Preplan-Plan-CoT), a framework that introduces an explicit pro...

While Reinforcement Learning with Verifiable Rewards (RLVR) is effective for deterministically checkable tasks, many vision-language tasks are partially verifiable, demanding multi-criteria supervision (e.g., perceptual details, reasoning steps, and constraints). Rubrics provide a natural interface for this fine-grained supervision, but their effectiveness depends on the execution accuracy during online RL. We propose Reinforcement Learning with Robust Rubric Rewards ($\text{RLR}^3$), extending RLVR from task-level verification to criterion-level verification. $\text{RLR}^3$ routes instance-s...

Misinformation verification increasingly occurs in public, fast-moving, and multilingual online settings, where static benchmarks provide an incomplete measure of model reliability. We introduce CommunityFact, a refreshable benchmark for misinformation detection in the wild, with three major goals: coverage, granularity, and redistributability. This release contains 15,992 standalone claims across five languages and two domains. We evaluate ten LLMs under varying inference-time capabilities, including thinking and web-search. Our results show that closed-input verification remains challenging...

https://preview.redd.it/ixbbh3qmuw3h1.png?width=1912&format=png&auto=webp&s=c4d9945b9c06d842e139523a958051b6172ef607 Solid model so far

Semi-structured knowledge bases (SKBs) embed textual documents in a typed graph of entities and relations, and underpin applications such as product search, academic paper search, and precision-medicine inquiries. Existing hybrid retrieval systems on SKBs either use the graph only for query expansion, mix textual and structural branches under a global weighting, or rely on fine-tuned graph-traversal generators. We present GRASP, a three-stage SKB retrieval framework unifying plan-based graph retrieval, plan-conditioned fusion with a dense retriever, and a fine-tuned reranker over the fused ca...

Today we're introducing dynamic workflows in Claude Code. Claude now writes its own orchestration scripts, fans work out across tens to hundreds of parallel subagents in a single session, and verifies its own results before anything reaches you. Work you'd normally plan in quarters can finish in days. Built for the tasks a single pass can't handle: codebase-wide bug hunts, security and optimization audits, large migrations and language ports, and high-stakes work where you want adversarial agents trying to break the answer before you see it. Progress is checkpointed, so long runs survive int...

Entity tracking (ET), the ability to keep track of states, is a fundamental skill that underlies complex reasoning. An increasing amount of work investigates how transformer language models (LMs) solve entity binding $\textit{without}$ state changes. However, there is limited understanding of how non-toy LMs address ET problems of realistic difficulties expressed in natural language. To this end, we investigate the mechanisms underlying ET in more complex scenarios featuring multiple state-changing operations. We find that LMs do not incrementally track world states across tokens or query-rel...

How does reinforcement learning shape a language model's internal representations? We present evidence that RL recruits a pre-existing representation of functional welfare: an estimate of how well or badly the system is doing, relative to its goals. We train several language models in a novel, semantically neutral maze environment. We then extract concept vectors for rewarded and punished trajectories, and evaluate those vectors in settings unrelated to the maze environment. The punishment vector behaves like a representation of negative welfare: it promotes failure and impossibility tokens, ...

Here’s why Anthropic and OpenAI are on board with Illinois safety testing.

Vision-Language Models (VLMs) often struggle with robust 3D spatial reasoning. Prevailing methods that rely on fine-tuning with 3D visual question-answering (VQA) datasets may overfit dataset-specific biases, while integrating specialized 3D visual encoders is often inflexible and cumbersome. In this paper, we argue that genuine spatial understanding should emerge from learning fundamental geometric priors, not only from high-level VQA supervision. We propose GASP (Geometric-Aware Spatial Priors), a framework that injects these priors directly into the LLM's transformer layers. GASP employs a...

The new Opus model comes with a tool called Dynamic Workflows, for coordinating swarms of subagents.

An upgrade to our Opus class of models, with stronger performance across coding, agentic tasks, and professional work, and the consistency to handle long-running work.

Anthropic is releasing Claude Opus 4.8 on Thursday, and the company is touting the model's "honesty." According to Anthropic, it trains "all [its] models to be honest - for instance, to avoid making claims that they can't support." But it notes that "a general problem with AI models is that they sometimes jump to conclusions, confidently presenting their work as making progress despite thin evidence." The AI lab claims that early testers have found that Opus 4.8 "is more likely to flag uncertainties about its work and less likely to make unsupported claims." In the company's evaluations, Opus...

We use a mean-field-based transformer model to theoretically investigate how auxiliary variables, such as positional encoding, prevent mode collapse of self-attention mechanisms. The use of mean-field transformers to analyze the properties of self-attention mechanisms has garnered significant attention in recent years due to their ability to comprehensively analyze token interactions. However, analysis of this simple model suggests that mode collapse, where token distributions degenerate to a single point, occurs during long inferences (i.e., many layers), indicating a discrepancy with realit...

While Multi-Agent Systems (MAS) empower Large Language Models to tackle complex reasoning tasks through collaborative interaction, optimizing their dynamics remains a formidable challenge due to the discrete, non-differentiable nature of the computation graph and the sparsity of global supervisory signals. Existing black-box optimizers struggle to attribute trajectory-level failure to specific local components, resulting in inefficient, high-variance exploration. We argue that tractable MAS optimization needs structural inductive biases to disentangle error signals. We propose temporal and st...